Phytochemicals, Antioxidant and Antimicrobial Potential of Ethnomedicinal Plants of Sikkim Himalaya

In the present study, four important ethnomedicinal plants of Sikkim Himalaya viz., Astilbe rivularis Buch- Ham ex. D. Don, Eupatorium adenophorum Spreng., Bergenia ciliata (Haw.) Sternb and Artemisia vulgaris L. were investigated to ensure its ethno pharmacological potency. The methanolic root extracts selected for total phenolic content, flavonoid antioxidant antimicrobial activities. Among tested extracts, extract contained highest content (911.4±0.124 mg gallic acid equivalents/g extract) showed exceptional activity in 2,2-diphenyl-1-picrylhydrazyl 2,2-azinobis (3-ethylbenzothiazoline-6-sulfonic assays with halfmaximal inhibitory concentration value 10 μg/ml 1.0 μg/ml, respectively. minimum was also found be lowest gram-negative bacteria Escherichia coli (600 μg/ml) actinomycetes Streptomyces sp. (800 μg/ml), suggesting high effective potency against microbes. further compounds using performance liquid chromatography. contain substantial amount bergenin, acid, chlorogenic catechin, p-coumeric m-coumeric acid. conclusion, this study gives scientific evidence on biological activities plant species recommends as candidate pharmaceutical drug development.